Description

2-Benzofurancarbonyl Chloride, 5-Chloro- (9Ci) is a specialized benzofuran derivative that serves as a critical acylating agent and high-value synthetic intermediate in advanced organic synthesis. Its molecular structure, featuring both a reactive acid chloride group and a halogenated benzofuran core, makes it indispensable for constructing complex heterocyclic frameworks. This compound is primarily sought after by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel benzofuran-based drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Serves as a monomer or precursor for advanced polymers and functional materials with specific optical or electronic properties.
• Organic Synthesis: Acts as a versatile acylating agent to introduce the 5-chlorobenzofuran-2-carbonyl moiety into more complex molecular architectures.
• Chemical Research: Utilized in academic and industrial R&D for methodological studies and the exploration of new chemical reactions.

Basic Information

Product Name	2-Benzofurancarbonyl Chloride, 5-Chloro- (9Ci)
CAS No.	474070-08-1
Molecular Formula	C9H4Cl2O2
Molecular Weight	215.04 g/mol
Synonyms	5-Chloro-1-benzofuran-2-carbonyl chloride; 5-Chlorobenzofuran-2-carbonyl chloride; 5-Chloro-2-benzofurancarbonyl chloride; 5-Chloro-2-benzofuranyl carbonyl chloride; 5-Chloro-2-benzofuroyl chloride; 5-Chloro-coumarone-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 2-Benzofurancarbonyl Chloride, 5-Chloro- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We maintain full traceability and documentation in line with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.