Description

N3-L-Lys(Fmoc)-Oh is a specialized, high-purity amino acid derivative featuring an azide (N3) functional group and an Fmoc-protected side chain. This compound is critical for advanced peptide synthesis, particularly in the construction of complex biomolecules via click chemistry and solid-phase methodologies. It is an essential building block for researchers and manufacturers in pharmaceutical development, proteomics, and bioconjugation, where precise molecular assembly is required.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the controlled, sequential assembly of peptides, especially those requiring orthogonal deprotection strategies.
• Click Chemistry Conjugation: The azide group enables efficient, selective Huisgen 1,3-dipolar cycloaddition with alkynes for labeling, bioconjugation, and creating peptide-drug conjugates.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the research and development of novel therapeutic peptides and peptidomimetics.
• Chemical Biology Probes: Used to synthesize tagged peptides for studying protein-protein interactions, enzyme activity, and cellular localization.
• Material Science: Incorporation into functionalized polymers or surfaces to create bioactive materials.

Basic Information

Product Name	N3-L-Lys(Fmoc)-Oh
CAS No.	473430-12-5
Molecular Formula	C21H22N4O4
Molecular Weight	394.43 g/mol
Synonyms	Fmoc-Lys(N3)-OH; N-α-Fmoc-N-ε-azido-L-lysine; Fmoc-L-lysine(N3)-OH; Azido-L-lysine(Fmoc); Nε-Azido-Nα-Fmoc-L-lysine; (2S)-6-Azido-2-[(9H-fluoren-9-ylmethoxy)carbonylamino]hexanoic acid; Fmoc-Lys(N3)-OH; Fmoc-ε-azido-L-lysine
EINECS	Contact for details

Quality Control

Our N3-L-Lys(Fmoc)-Oh is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and cGMP applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent internal specifications to support our customers' needs in regulatory filing and process development.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This product is hygroscopic (moisture-sensitive) and should be allowed to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.