Description

(3,5-Difluoro-4-(Methylthio)Phenyl)Methanol is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its difluoro and methylthio substituents impart unique electronic and steric properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and fungicides, leveraging its fluorinated aromatic core.
• Liquid Crystal Materials: Serves as a precursor in the synthesis of fluorinated components for advanced display technologies.
• Organic Electronic Materials: Employed in the research and development of organic semiconductors and charge-transport materials.
• Cross-Coupling Reactions: The benzylic alcohol functionality allows for further derivatization via oxidation or substitution, making it valuable in palladium-catalyzed and other metal-mediated couplings.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up services for specialized chemical entities.

Basic Information

Product Name	(3,5-Difluoro-4-(Methylthio)Phenyl)Methanol
CAS No.	473299-50-2
Molecular Formula	C8H8F2OS
Molecular Weight	190.21 g/mol
Synonyms	4-(Hydroxymethyl)-2,6-difluoro-1-(methylthio)benzene; (3,5-Difluoro-4-methylsulfanylphenyl)methanol; 2,6-Difluoro-4-(methylthio)benzyl alcohol; 1-(3,5-Difluoro-4-(methylthio)phenyl)methanol; Benzenemethanol, 3,5-difluoro-4-(methylthio)-; 3,5-Difluoro-4-(methylthio)benzyl alcohol
EINECS	Contact for details

Quality Control

Our (3,5-Difluoro-4-(Methylthio)Phenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with exacting standards for fine chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.