Description

2H-Benzimidazol-2-One,1,3-Dihydro-5-Isothiocyanato-(9Ci) is a specialized heterocyclic organic compound featuring a reactive isothiocyanate group, making it a valuable chemical intermediate for advanced synthesis. This compound is critical for researchers and manufacturers requiring precise molecular building blocks for pharmaceuticals and agrochemicals. It is primarily utilized in the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel benzimidazole-derived drug candidates, particularly for antiviral and anticancer therapies.
• Agrochemical Research: Used in the development of new fungicides and pesticides, leveraging its heterocyclic core for biological activity.
• Chemical Biology Probe: The reactive isothiocyanate group allows for selective conjugation with amines, useful in creating fluorescent probes or affinity labels for protein studies.
• Material Science: Serves as a precursor for advanced polymers and functional materials requiring specific heterocyclic architectures.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.

Basic Information

Product Name	2H-Benzimidazol-2-One,1,3-Dihydro-5-Isothiocyanato-(9Ci)
CAS No.	471938-44-0
Molecular Formula	C8H5N3OS
Molecular Weight	191.21 g/mol
Synonyms	5-Isothiocyanato-1,3-dihydro-2H-benzimidazol-2-one; 1,3-Dihydro-5-isothiocyanato-2H-benzimidazol-2-one; 2H-Benzimidazol-2-one, 1,3-dihydro-5-isothiocyanato-; 5-Isothiocyanatobenzimidazolone; Benzimidazolone, 5-isothiocyanato-
EINECS	Contact for details

Quality Control

Our production of 2H-Benzimidazol-2-One,1,3-Dihydro-5-Isothiocyanato-(9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure full traceability and compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.