Description

3-(Trifluoromethoxy)Phenylisothiocyanate is a specialized aromatic isothiocyanate derivative, distinguished by the presence of a trifluoromethoxy substituent. This compound is a high-value synthetic intermediate prized for its role in constructing complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the life sciences and specialty chemical sectors for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-targeted therapeutic research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides with enhanced activity and environmental profiles.
• Ligand and Probe Development: Serves as a versatile reagent for creating chemical probes, fluorescent tags, and ligands for biological target identification and validation.
• Material Science Precursor: Employed in the synthesis of advanced polymers and functional materials where the trifluoromethoxy group imparts specific electronic or hydrophobic properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	3-(Trifluoromethoxy)Phenylisothiocyanate
CAS No.	471937-78-7
Molecular Formula	C8H4F3NOS
Molecular Weight	219.18 g/mol
Synonyms	3-(Trifluoromethoxy)phenyl isothiocyanate; 1-Isothiocyanato-3-(trifluoromethoxy)benzene; m-(Trifluoromethoxy)phenyl isothiocyanate; 3-Trifluoromethoxyphenyl isothiocyanate; [3-(Trifluoromethoxy)phenyl]isothiocyanate; 3-(Trifluoromethoxy)benzenisothiocyanate
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethoxy)Phenylisothiocyanate is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.