Description

(5-Bromo-3-Fluoro-2-Methoxyphenyl)Methanol is a high-purity, multi-functional aromatic alcohol building block of significant importance in advanced organic synthesis. Its value lies in the strategic positioning of bromo, fluoro, and methoxy substituents on the phenyl ring, which enables precise structural modifications and the introduction of key pharmacophores. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and oncology drugs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the fluorine and bromine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing sophisticated ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Precursor: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and functional handles.
• Chemical Biology Probe: Utilized in medicinal chemistry for structure-activity relationship (SAR) studies and as a building block for fluorescent tags or molecular probes.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards for regulated markets.

Basic Information

Product Name	(5-Bromo-3-Fluoro-2-Methoxyphenyl)Methanol
CAS No.	470668-69-0
Molecular Formula	C8H8BrFO2
Molecular Weight	235.05 g/mol
Synonyms	5-Bromo-3-fluoro-2-methoxybenzyl alcohol; (5-Bromo-3-fluoro-2-methoxyphenyl)methanol; 2-Methoxy-5-bromo-3-fluorobenzyl alcohol; 5-Bromo-3-fluoro-o-anisyl alcohol; Benzenemethanol, 5-bromo-3-fluoro-2-methoxy-; 470668-69-0; (5-Bromo-3-fluoro-2-methoxyphenyl)methanol
EINECS	Contact for details

Quality Control

Our (5-Bromo-3-Fluoro-2-Methoxyphenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.