Description

2-Amino-9-β-L-Arabinofuranosyl-1,9-Dihydro-6H-Purin-6-One is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis and study of novel antiviral and anticancer therapeutics. It is primarily required by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of nucleoside-based drugs. Our supply ensures consistent quality and reliable availability for critical research and production processes.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of novel antiviral agents.
• Antiviral Drug Research: Reference standard and active component in the study of nucleoside analog therapies targeting viral polymerases.
• Oncology Research: Investigated for its potential role in the synthesis of chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleoside metabolism.
• Process Development: Serves as a critical raw material in the scale-up and optimization of API (Active Pharmaceutical Ingredient) manufacturing processes.
• Analytical Standard: High-purity grade material for use in HPLC, LC-MS, and NMR as a calibration or identification standard.

Basic Information

Product Name	2-Amino-9-β-L-Arabinofuranosyl-1,9-Dihydro-6H-Purin-6-One
CAS No.	469887-93-2
Molecular Formula	C₁₀H₁₃N₅O₅
Molecular Weight	283.24 g/mol
Synonyms	2-Amino-9-β-L-arabinofuranosyl-1,9-dihydro-6H-purin-6-one; 2-Amino-ara-G; 2-Amino-9-β-D-arabinofuranosylguanine (enantiomer); β-L-2-Aminoguanine arabinoside; 2-Amino-L-arabinofuranosylguanine; 9-[(2R,3S,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,9-dihydro-6H-purin-6-one; L-2-Aminoguanosine analog; Ara-G Amine Derivative
EINECS	Contact for details

Quality Control

Our 2-Amino-9-β-L-Arabinofuranosyl-1,9-Dihydro-6H-Purin-6-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.