Description

1-(3,5-Difluorophenyl)Ethanol is a versatile fluorinated aromatic alcohol building block, identified by CAS NO 467223-90-1. Its value lies in the strategic placement of fluorine atoms on the phenyl ring, which significantly influences the electronic and steric properties of downstream molecules, making it a critical intermediate in advanced synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides where the difluorophenyl moiety contributes to efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorinated liquid crystals for high-performance displays.
• Advanced Polymer Chemistry: Incorporated as a monomer or chain modifier to create specialty polymers with unique thermal and chemical resistance properties.
• Organic Synthesis Building Block: Employed in asymmetric synthesis, cross-coupling reactions, and the preparation of complex ligands for catalysis.
• Material Science Research: Utilized in the development of novel organic electronic materials and coatings.

Basic Information

Product Name	1-(3,5-Difluorophenyl)Ethanol
CAS No.	467223-90-1
Molecular Formula	C8H8F2O
Molecular Weight	158.15 g/mol
Synonyms	α-(3,5-Difluorophenyl)ethanol; (3,5-Difluorophenyl)methylcarbinol; 1-(3,5-Difluorophenyl)ethyl alcohol; 3,5-Difluoro-α-methylbenzyl alcohol; (RS)-1-(3,5-Difluorophenyl)ethanol; rac-1-(3,5-Difluorophenyl)ethanol; 3,5-Difluoro-α-methylbenzenemethanol
EINECS	Contact for details

Quality Control

Our 1-(3,5-Difluorophenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.