Description

3-(4-Fluorophenyl)-5-Methyl-4-Isoxazolecarbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its role as a versatile acylating agent, enabling the efficient construction of complex heterocyclic scaffolds. This compound is critically needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those containing the isoxazole pharmacophore.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides.
• Chemical Research: Serves as a versatile reagent in academic and industrial laboratories for exploring new chemical reactions and creating specialized libraries of compounds.
• Material Science: Potential precursor for the development of advanced polymers or functional materials with specific optical or electronic properties.
• Peptide Mimetics: Can be utilized to introduce the isoxazole moiety into peptide chains, modifying their biological activity and stability.

Basic Information

Product Name	3-(4-Fluorophenyl)-5-Methyl-4-Isoxazolecarbonyl Chloride
CAS No.	465514-05-0
Molecular Formula	C11H7ClFNO2
Molecular Weight	239.63 g/mol
Synonyms	4-Isoxazolecarbonyl chloride, 3-(4-fluorophenyl)-5-methyl-; 5-Methyl-3-(4-fluorophenyl)isoxazole-4-carbonyl chloride; 3-(p-Fluorophenyl)-5-methyl-4-isoxazolecarbonyl chloride; 3-(4-Fluorophenyl)-5-methylisoxazole-4-carbonyl chloride; 465514-05-0; 4-Carbonyl chloride-3-(4-fluorophenyl)-5-methylisoxazole
EINECS	Contact for details

Quality Control

Our 3-(4-Fluorophenyl)-5-Methyl-4-Isoxazolecarbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.