Description

4-Phenylbutanoyl Chloride is a versatile and reactive acid chloride derivative of 4-phenylbutyric acid. This compound serves as a critical building block in organic synthesis, enabling the efficient introduction of the 4-phenylbutanoyl moiety into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of amides, esters, and other functionalized intermediates.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting metabolic and neurological disorders.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require the phenylbutyric acid backbone.
• Peptide Mimetics & Modifications: Employed to acylate amino groups or hydroxyl groups in amino acids and peptides to create novel analogs with enhanced properties.
• Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialty polyamides, polyesters, and coatings with specific aromatic characteristics.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing aromatic cores used in advanced electronic and display materials.
• Chemical Research & Development: A valuable tool for academic and industrial R&D labs exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	4-Phenylbutanoyl Chloride
CAS No.	464917-79-1
Molecular Formula	C10H11ClO
Molecular Weight	182.65 g/mol
Synonyms	4-Phenylbutyryl Chloride; 4-Phenylbutanoic Acid Chloride; γ-Phenylbutyryl Chloride; Benzenebutanoyl Chloride; 4-Phenylbutyric Acid Chloride; 4-Phenylbutanoyl Chloride; 4-Phenyl-butyrylchloride; Phenylbutyryl Chloride
EINECS	Contact for details

Quality Control

Our 4-Phenylbutanoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards expected in pharmaceutical and fine chemical supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.