Description

N3-Peg1-Ch2Ch2Nh2 is a heterobifunctional polyethylene glycol (PEG) linker featuring an azide (N3) group and a primary amine (NH2) group, separated by a short ethylene glycol spacer. This compound is a critical building block in bioconjugation and click chemistry, enabling the efficient and selective coupling of biomolecules, polymers, and surfaces. It is essential for researchers and manufacturers in pharmaceutical development, proteomics, and advanced materials science, where precise and stable cross-linking is required.

Application

• Bioconjugation and Antibody-Drug Conjugate (ADC) Development: Used to link cytotoxic drugs, fluorophores, or other payloads to antibodies, proteins, or peptides via the amine-reactive group, with the azide enabling subsequent bioorthogonal click chemistry modifications.
• Surface Functionalization and Biomaterial Engineering: Employed to modify nanoparticles, hydrogels, or diagnostic chip surfaces to introduce amine or azide functionalities for further biomolecule immobilization.
• Polymer and Dendrimer Synthesis: Serves as a versatile monomer or cross-linker for creating functionalized PEG-based polymers with tailored reactive sites.
• Proteomics and Chemical Biology: Acts as a key reagent for labeling, pull-down assays, and activity-based protein profiling (ABPP) to study protein function and interactions.
• Diagnostic Reagent Formulation: Utilized in the development of immunoassays and biosensors to create stable conjugates between detection molecules and solid supports.

Basic Information

Product Name	N3-Peg1-Ch2Ch2Nh2
CAS No.	464190-91-8
Molecular Formula	C7H15N5O2
Molecular Weight	201.23 g/mol
Synonyms	2-(2-(2-Azidoethoxy)ethoxy)ethanamine; Azido-PEG2-amine; N3-PEG2-NH2; 1-Azido-3,6-dioxaoctan-8-amine; 2,5,8-Trioxa-11-azadodecan-12-amine, 11-azido-; Azido-PEG2-amine HCl salt (if applicable); PEG2 azide amine; Heterobifunctional PEG linker, N3-PEG2-NH2
EINECS	Contact for details

Quality Control

Our N3-Peg1-Ch2Ch2Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance for sensitive research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. For long-term storage under inert atmosphere, consider storing under argon or nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.