Description

(3α,5β,6α)-6-Ethyl-3-Hydroxy-7-Oxo-Cholan-24-Oicacid Ethylester is a high-purity, synthetic bile acid derivative with a defined stereochemistry. This compound serves as a critical pharmaceutical intermediate and a valuable reference standard for research and quality control laboratories. It is primarily needed by manufacturers and R&D teams in the pharmaceutical and biotechnology sectors for the development and production of advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel steroidal drugs and therapeutic agents targeting metabolic and liver disorders.
• Reference Standard: Used for analytical method development, validation, and quality control testing in pharmaceutical manufacturing to ensure product purity and consistency.
• Biochemical Research: Employed in academic and industrial research to study bile acid metabolism, receptor interactions, and related biological pathways.
• Process Development: Serves as a starting material or intermediate for optimizing synthetic routes and scaling up production of complex steroidal molecules.
• Active Pharmaceutical Ingredient (API) Synthesis: Integral to the multi-step synthesis of proprietary APIs where specific stereochemistry is required for biological activity.

Basic Information

Product Name	(3α,5β,6α)-6-Ethyl-3-Hydroxy-7-Oxo-Cholan-24-Oicacid Ethylester
CAS No.	459789-97-0
Molecular Formula	C₂₆H₄₂O₅
Molecular Weight	434.61 g/mol
Synonyms	6α-Ethyl-3α,7α-dihydroxy-5β-cholan-24-oic acid ethyl ester; Ethyl 6α-ethyl-3α,7α-dihydroxy-5β-cholan-24-oate; 6-Ethylchenodeoxycholic acid ethyl ester; 6α-Ethyl-CDCA ethyl ester; 6-ECDCA ethyl ester; (3α,5β,6α,7α)-6-Ethyl-3,7-dihydroxycholan-24-oic acid ethyl ester; Ethyl 6-ethyl-3,7-dihydroxy-5β-cholan-24-oate
EINECS	Contact for details

Quality Control

Our (3α,5β,6α)-6-Ethyl-3-Hydroxy-7-Oxo-Cholan-24-Oicacid Ethylester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and conformity to customer specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support audits for cGMP and ISO compliance where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.