Description

1H-Imidazole-4-Carbonyl Chloride, 5-Propyl- (9Ci) is a specialized heterocyclic building block featuring a reactive carbonyl chloride group on the imidazole core. This compound is critical for the synthesis of complex molecules, enabling the introduction of the imidazole pharmacophore into target structures with high precision. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting enzymes and receptors where the imidazole moiety is essential for binding.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that incorporate heterocyclic structures for enhanced activity.
• Chemical Biology Probes: Serves as a reagent for modifying peptides, proteins, or other biomolecules to study biological pathways or create diagnostic tools.
• Material Science Research: Employed in the development of advanced polymers, ligands for catalysis, or organic electronic materials with specific functional properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services for clients in life sciences.

Basic Information

Product Name	1H-Imidazole-4-Carbonyl Chloride, 5-Propyl- (9Ci)
CAS No.	459432-76-9
Molecular Formula	C7H9ClN2O
Molecular Weight	172.61 g/mol
Synonyms	5-Propyl-1H-imidazole-4-carbonyl chloride; 5-Propyl-1H-imidazole-4-carboxylic acid chloride; 5-n-Propyl-1H-imidazole-4-carbonyl chloride; 4-Carbonyl chloride-5-propylimidazole; 1H-Imidazole-4-carbonyl chloride, 5-propyl-; 459432-76-9; 5-Propylimidazole-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 1H-Imidazole-4-Carbonyl Chloride, 5-Propyl- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.