Description

(4'-Trifluoromethylbiphenyl-4-Yl)-Methanol is a high-purity, specialized organic building block featuring a biphenyl core substituted with a trifluoromethyl group and a hydroxymethyl group. This compound is valued for its role as a critical intermediate in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for constructing rigid, conjugated structures used in electronic displays and organic light-emitting diodes (OLEDs).
• Ligand & Catalyst Development: The biphenyl scaffold with functional handles is useful for creating chiral ligands and organocatalysts for asymmetric synthesis.
• Polymer & Advanced Material Science: Incorporated as a monomer or cross-linking agent to create high-performance polymers with specific thermal and optical properties.
• Chemical Biology & Probe Synthesis: Utilized in the design and synthesis of molecular probes and tags for biochemical and diagnostic applications.

Basic Information

Product Name	(4'-Trifluoromethylbiphenyl-4-Yl)-Methanol
CAS No.	457889-46-2
Molecular Formula	C14H11F3O
Molecular Weight	252.23 g/mol
Synonyms	[4-(Trifluoromethyl)[1,1'-biphenyl]-4-yl]methanol; 4'-(Trifluoromethyl)-[1,1'-biphenyl]-4-methanol; (4'-Trifluoromethyl-[1,1'-biphenyl]-4-yl)-methanol; α-(4'-Trifluoromethylbiphenyl-4-yl)methanol; 4-(Hydroxymethyl)-4'-(trifluoromethyl)biphenyl; Biphenyl-4-methanol, 4'-(trifluoromethyl)-; (4'-Trifluoromethylbiphenyl-4-yl)methanol
EINECS	Contact for details

Quality Control

Our (4'-Trifluoromethylbiphenyl-4-Yl)-Methanol is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.