Description

Cholestan-6-One, 2,3,14,20,22,25-Hexahydroxy-, (2β,3β,5β,22R)- is a highly functionalized steroidal ketone derivative, representing a key advanced intermediate in the synthesis of complex bioactive molecules. Its precise stereochemistry and multiple hydroxyl groups make it a valuable scaffold for pharmaceutical research and development, particularly for targeting specific metabolic pathways. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, including potential treatments for metabolic and hormonal disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical building block for the synthesis of novel steroid-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in metabolic pathway studies and enzyme inhibition assays.
• Hormone Analog Development: Acts as a precursor in the research and development of synthetic hormone analogs and receptor modulators.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry projects and structure-activity relationship (SAR) studies.
• Process Chemistry: Utilized in scaling up synthetic routes for potential drug candidates during preclinical and early development phases.

Basic Information

Item	Detail
Product Name	Cholestan-6-One, 2,3,14,20,22,25-Hexahydroxy-, (2β,3β,5β,22R)-
CAS No.	457603-63-3
Molecular Formula	C27H46O7
Molecular Weight	482.66 g/mol
Synonyms	(2β,3β,5β,22R)-2,3,14,20,22,25-Hexahydroxycholestan-6-one; 2,3,14,20,22,25-Hexahydroxy-5β-cholestan-6-one; Polyhydroxylated Cholestane Derivative; Hexahydroxy Cholestanone; Steroidal Polyol Ketone; CAS 457603-63-3
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material that meets high-purity requirements for research and development use. Certificates of Analysis (COA) are available upon request, detailing key parameters such as identity, purity, and impurity profiles. Our commitment to quality supports reliable and reproducible results in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.