Description

Isoxazolo[5,4-B]Pyridine-5-Carbonyl Chloride, 3-Methyl- (9Ci) is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-infective therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a building block for creating advanced organic electronic materials, ligands for catalysis, and specialty polymers.
• Chemical Biology & Probe Development: Employed in the design and synthesis of chemical probes for studying biological pathways and protein function.
• Academic & Contract Research: Essential for synthetic methodology development and exploratory chemistry in university and CRO (Contract Research Organization) laboratories.
• Scale-up & Process Chemistry: Used in the optimization and kilogram-scale production of target molecules for pre-clinical and clinical trials.

Basic Information

Product Name	Isoxazolo[5,4-B]Pyridine-5-Carbonyl Chloride, 3-Methyl- (9Ci)
CAS No.	445496-31-1
Molecular Formula	C9H5ClN2O2
Molecular Weight	208.60 g/mol
Synonyms	3-Methylisoxazolo[5,4-b]pyridine-5-carbonyl chloride; 3-Methylisoxazolo[5,4-b]pyridine-5-carboxylic acid chloride; 3-Methyl-[1,2]oxazolo[5,4-b]pyridine-5-carbonyl chloride; 445496-31-1; Isoxazolo[5,4-b]pyridine-5-carbonyl chloride, 3-methyl-; 3-Methylisoxazolo[5,4-b]pyridine-5-carboxyl chloride
EINECS	Contact for details

Quality Control

Our Isoxazolo[5,4-B]Pyridine-5-Carbonyl Chloride, 3-Methyl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by modern analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.