Description

Nicotinamide Riboside Triflate is a high-purity triflate salt derivative of nicotinamide riboside, a key precursor to nicotinamide adenine dinucleotide (NAD+). This compound is valued for its enhanced stability and solubility profile compared to other salt forms, making it a critical intermediate in advanced pharmaceutical and nutraceutical synthesis. It is primarily sought by research institutions and manufacturers in the life sciences sector for developing NAD+ boosting supplements, metabolic research, and high-value active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of next-generation NAD+ precursor drugs and supplements.
• Nutraceutical Manufacturing: Used in the production of high-purity, stabilized nicotinamide riboside (NR) for dietary supplements aimed at cellular health and metabolism.
• Biochemical Research: Employed as a standard or reagent in metabolic pathway studies, aging research, and sirtuin activity assays.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for HPLC or LC-MS method development and validation.
• Cosmeceutical Formulations: Incorporated into advanced skincare products targeting cellular repair and anti-aging benefits.
• Pre-clinical & Clinical Trial Materials: Supplied as a GMP-grade intermediate for the production of materials used in regulatory studies.

Basic Information

Product Name	Nicotinamide Riboside Triflate
CAS No.	445489-49-6
Molecular Formula	C13H19F3N2O8S
Molecular Weight	420.36 g/mol
Synonyms	Nicotinamide Riboside Trifluoromethanesulfonate; NR Triflate; 1-(β-D-Ribofuranosyl)nicotinamide Triflate; 3-Carbamoyl-1-(β-D-ribofuranosyl)pyridinium Trifluoromethanesulfonate; Nicotinamide Riboside Trifluoromethanesulphonate; Niagen Triflate Salt; NAD+ Precursor Triflate Salt
EINECS	Contact for details

Quality Control

Our Nicotinamide Riboside Triflate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and heavy metals. We provide Certificates of Analysis (COA) with every shipment, detailing all specifications. Production can be aligned with cGMP guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere or in a controlled humidity environment to maintain stability and prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.