Description

3,7-Anhydro-4-Azido-1,2,4-Trideoxy-5,6,8-Tris-o-(Phenylmethyl)-1-(Trimethylsilyl)-D-Glycero-D-Gulo-Oct-1-Ynitol is a sophisticated, multi-functional carbohydrate derivative designed for advanced synthetic chemistry. This compound is a critical high-purity building block for the synthesis of complex nucleoside analogs, glycoconjugates, and other biologically active molecules. It is essential for researchers and process chemists in the pharmaceutical, biotechnology, and agrochemical industries who require reliable, high-quality intermediates for drug discovery and development programs.

Application

• Key Intermediate in Nucleoside Synthesis: Serves as a protected, functionalized precursor for the development of novel antiviral and anticancer nucleoside analogs.
• Glycoconjugate Chemistry: Used in the construction of complex oligosaccharides and glycopeptides for vaccine development and glycobiology research.
• Medicinal Chemistry & Drug Discovery: Provides a versatile scaffold for structure-activity relationship (SAR) studies and the generation of focused compound libraries.
• Agrochemical Research: Employed in the synthesis of novel carbohydrate-based active ingredients with potential herbicidal or insecticidal properties.
• Chemical Biology Probes: The azido group enables click chemistry (e.g., CuAAC) for labeling, imaging, and studying biological processes.
• Process Chemistry & Scale-up: Supplied under GMP-like conditions for use in the development and production of Active Pharmaceutical Ingredients (APIs).

Basic Information

Item	Details
Product Name	3,7-Anhydro-4-Azido-1,2,4-Trideoxy-5,6,8-Tris-o-(Phenylmethyl)-1-(Trimethylsilyl)-D-Glycero-D-Gulo-Oct-1-Ynitol
CAS No.	443916-28-7
Molecular Formula	C34H43N3O4Si
Molecular Weight	585.81 g/mol
Synonyms	1,2,4-Trideoxy-4-azido-3,7-anhydro-5,6,8-tris-O-benzyl-1-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol; 4-Azido-3,7-anhydro-1,2,4-trideoxy-5,6,8-tris-O-(phenylmethyl)-1-(trimethylsilyl)-D-glycero-D-gulo-oct-1-ynitol; Benzyl-protected azido sugar intermediate; TMS-protected azido carbohydrate; CAS 443916-28-7
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under stringent quality systems. We provide comprehensive analytical data to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, NMR, and MS are supplied with each shipment. Our quality commitment aligns with ISO 9001 principles, and we can support development programs requiring materials produced under GMP-like controls.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) in a cool, dry, well-ventilated place. Due to its hygroscopic and light-sensitive nature, containers should be allowed to reach room temperature before opening to minimize moisture ingress. Keep away from strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.