Description

7-Deaza 2-C-Methyl-N6-Methyladenosine is a chemically modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and a key reference standard in the synthesis of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions, pharmaceutical companies, and CROs (Contract Research Organizations) engaged in medicinal chemistry, nucleotide-based drug discovery, and biochemical studies. The compound, identified by CAS number 443642-86-2, is valued for its role in probing enzyme mechanisms and developing targeted nucleotide analogs.

Application

• Medicinal Chemistry Research: A key intermediate in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Studies: Used as a substrate or inhibitor to study the activity and mechanism of adenosine-metabolizing enzymes, such as methyltransferases and kinases.
• Pharmaceutical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in drug manufacturing and regulatory submissions.
• Nucleotide Analog Development: Employed in the design of modified mRNA and oligonucleotides for therapeutic applications, including antisense and RNAi technologies.
• Academic Research: Utilized in university and institutional labs for fundamental research in chemical biology and nucleic acid chemistry.

Basic Information

Product Name	7-Deaza 2-C-Methyl-N6-Methyladenosine
CAS No.	443642-86-2
Molecular Formula	C12H16N6O4
Molecular Weight	308.29 g/mol
Synonyms	7-Deaza-2'-C-methyl-N6-methyladenosine; 2'-C-Methyl-7-deaza-N6-methyladenosine; 4-Amino-7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-5H-pyrrolo[3,2-d]pyrimidine; 7-Deaza-2'-C-methyladenosine, N6-methyl-; 2'-C-Methyl-7-deazaadenosine, N6-methyl-; Tubercidin analog, 2'-C-methyl-N6-methyl-
EINECS	Contact for details

Quality Control

Our 7-Deaza 2-C-Methyl-N6-Methyladenosine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.