Description

5-Methyl-7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine CAS NO 443642-53-3 is a high-purity nucleoside analog, a critical building block in pharmaceutical research and development. This compound is valued for its role as a key intermediate in the synthesis of novel antiviral and anticancer therapeutics. It is primarily sought by research institutions and pharmaceutical companies engaged in the discovery and development of nucleoside-based drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the development of therapeutics targeting viral polymerases and replication mechanisms.
• Oncology Research: Serves as a building block for creating potential chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate nucleoside metabolism pathways.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies to optimize the potency and selectivity of drug candidates.
• Process Development: Serves as a reference standard and starting material for scaling up synthetic routes under GMP conditions.

Basic Information

Product Name	5-Methyl-7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine
CAS No.	443642-53-3
Molecular Formula	C13H18N4O4
Molecular Weight	294.31 g/mol
Synonyms	4-Amino-5-methyl-7-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-7H-pyrrolo[2,3-d]pyrimidine; 7-[(2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 2'-C-Methyl-7-deaza-adenosine; 7-Deaza-2'-C-methyladenosine; 2'-C-Methyl-7-deazaadenosine; 2'-C-Methyl-tubercidin; Nucleoside analog intermediate
EINECS	Contact for details

Quality Control

Our 5-Methyl-7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with ICH guidelines and can provide material for GMP applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere when possible and opened only in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.