Description

7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is a high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel antiviral and anticancer agents, particularly in the development of nucleoside-based therapeutics. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the creation of next-generation drugs. The consistent quality and reliable supply of this material are paramount for ensuring the reproducibility and success of downstream synthetic processes.

Application

• Pharmaceutical Intermediate: A key synthetic precursor for the development of novel antiviral and anticancer nucleoside analogs.
• Antiviral Drug Research: Used in the R&D of therapeutics targeting viral polymerases and replication mechanisms.
• Oncology Research: Employed in the synthesis of experimental chemotherapeutic agents that interfere with DNA/RNA synthesis in cancer cells.
• Biochemical Tool Compound: Serves as a substrate or inhibitor in enzymatic studies and mechanistic biological research.
• Process Chemistry & Scale-Up: Utilized in route scouting, optimization, and pilot-scale production of active pharmaceutical ingredients (APIs).
• Custom Synthesis & Contract Manufacturing: A starting material for the custom synthesis of specialized nucleoside derivatives for client-specific projects.

Basic Information

Product Name	7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine
CAS No.	443642-48-6
Molecular Formula	C12H16N4O4
Molecular Weight	280.28 g/mol
Synonyms	2-Amino-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 2-Amino-7-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-7H-pyrrolo[2,3-d]pyrimidine; 7-(2-C-Methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-2-amine; β-D-Nucleoside analog intermediate; 2-Amino-7-(2-C-methyl-β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidin-2-Amine is manufactured under strict quality control protocols to ensure it meets the exacting standards required for pharmaceutical research. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to ensure product integrity, traceability, and consistency for critical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.