Description

N4-Cyclopropyl-7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidine-2,4-Diamine is a high-purity nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the creation of novel antiviral and anticancer therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of modified nucleosides and nucleotide prodrugs. The material is supplied with stringent quality control to ensure consistency and reliability for critical synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of investigational nucleoside-based antiviral agents.
• Antiviral Drug Discovery: Used in R&D for developing therapeutics targeting viral polymerases and replication mechanisms.
• Oncology Research: Employed in the development of nucleotide analogs designed to inhibit cancer cell proliferation.
• Biochemical Research: Acts as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism.
• Prodrug Synthesis: A key starting material for creating prodrug forms to enhance bioavailability and targeting.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	N4-Cyclopropyl-7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidine-2,4-Diamine
CAS No.	443642-41-9
Molecular Formula	C15H19N5O4
Molecular Weight	333.35 g/mol
Synonyms	2-Amino-4-(cyclopropylamino)-7-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-7H-pyrrolo[2,3-d]pyrimidine; 2,4-Diamino-7-[(2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-yl]-N4-cyclopropyl-7H-pyrrolo[2,3-d]pyrimidine; 7-(2-C-Methyl-β-D-ribofuranosyl)-N4-cyclopropyl-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine; β-D-Nucleoside analog intermediate; Cyclopropyl pyrrolopyrimidine nucleoside.
EINECS	Contact for details

Quality Control

Our N4-Cyclopropyl-7-(2-C-Methyl-β-D-Ribofuranosyl)-7H-Pyrrolo[2,3-D]Pyrimidine-2,4-Diamine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and stringent controls for residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible. For long-term storage, consider desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.