Description

4-(2-Oxo-2H-Chromen-3-Yl)-Benzoyl Chloride is a high-purity, reactive organic intermediate featuring a benzoyl chloride group attached to a coumarin core. This compound is valued for its dual functionality, enabling its use as a key building block in the synthesis of complex molecules for advanced applications. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibitors or possessing fluorescent properties for diagnostic applications.
• Agrochemical Synthesis: Serves as a building block for developing new-generation pesticides and herbicides, where the coumarin moiety can contribute to biological activity.
• Organic Light-Emitting Diodes (OLEDs): Used in the research and production of electron-transport or emissive layer materials due to the photophysical properties of the coumarin derivative.
• Fluorescent Probe & Sensor Development: Acts as a core structure for creating sensitive chemical sensors and biological imaging agents.
• Polymer & Material Science: Incorporated into specialty polymers to impart specific optical or chemical properties to advanced materials.
• Research & Development: Employed in academic and industrial R&D labs for exploring new chemical reactions and creating libraries of compounds for high-throughput screening.

Basic Information

Product Name	4-(2-Oxo-2H-Chromen-3-Yl)-Benzoyl Chloride
CAS No.	443289-29-0
Molecular Formula	C16H9ClO3
Molecular Weight	284.69 g/mol
Synonyms	3-(4-Chlorocarbonylphenyl)coumarin; 4-(2-Oxochromen-3-yl)benzoyl chloride; 3-(4-Chlorocarbonylphenyl)-2H-chromen-2-one; 4-(2-Oxo-2H-1-benzopyran-3-yl)benzoyl chloride; 3-(4-Chlorocarbonylphenyl)-2H-1-benzopyran-2-one; 4-Coumarin-3-yl-benzoyl chloride
EINECS	Contact for details

Quality Control

Our 4-(2-Oxo-2H-Chromen-3-Yl)-Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets precise customer specifications. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and reactive acid chloride nature, the container must be kept under an inert atmosphere (e.g., nitrogen or argon) and protected from moisture to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.