Description

2,4-Dichloro-5-[(3-Fluorobenzyl)Oxy]Aniline is a high-purity, multi-functional aromatic amine derivative designed for advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and agrochemical building block, enabling the development of novel active ingredients. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated and alkoxy-substituted aniline motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its dichloro and fluorobenzyloxy substituents for bioactivity.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers, dyes, and liquid crystals with tailored optical or electronic properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Buchwald-Hartwig amination) and as a precursor for heterocyclic compounds like benzoxazoles and quinazolines.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory compliance in API manufacturing.

Basic Information

Item	Detail
Product Name	2,4-Dichloro-5-[(3-Fluorobenzyl)Oxy]Aniline
CAS No.	439095-33-7
Molecular Formula	C13H10Cl2FNO
Molecular Weight	290.13 g/mol
Synonyms	5-[(3-Fluorobenzyl)oxy]-2,4-dichloroaniline; 2,4-Dichloro-5-[(3-fluorophenyl)methoxy]benzenamine; 2,4-Dichloro-5-(3-fluorobenzyloxy)aniline; 439095-33-7; Benzenamine, 2,4-dichloro-5-[(3-fluorophenyl)methoxy]-; 3-Fluorobenzyl 2,4-dichloro-5-aminophenyl ether
EINECS	Contact for details

Quality Control

Our 2,4-Dichloro-5-[(3-Fluorobenzyl)Oxy]Aniline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, GC for residual solvents, and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical and agrochemical applications. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.