Description

(4-Ethoxy-2,6-Difluorophenyl)Methanol is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in the strategic combination of an ethoxy group and fluorine atoms on the phenyl ring, which allows for precise modulation of electronic and steric properties in target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring fluorinated compounds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a crucial building block in the production of advanced herbicides, fungicides, and insecticides, where the difluoroethoxy moiety can improve efficacy and environmental profile.
• Liquid Crystal Materials: Used in the research and manufacture of fluorinated liquid crystals for display technologies, contributing to improved dielectric anisotropy and stability.
• Organic Electronic Materials: Acts as a precursor for functionalized aromatic cores in the development of organic semiconductors, OLEDs, and other electronic materials.
• Cross-Coupling Reactions: The benzylic alcohol functionality can be activated for use in palladium-catalyzed cross-coupling reactions to create complex biaryl structures.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific fluorinated aromatic units.

Basic Information

Item	Details
Product Name	(4-Ethoxy-2,6-Difluorophenyl)Methanol
CAS No.	438050-23-8
Molecular Formula	C9H10F2O2
Molecular Weight	188.17 g/mol
Synonyms	2,6-Difluoro-4-ethoxybenzyl alcohol; (2,6-Difluoro-4-ethoxyphenyl)methanol; 4-Ethoxy-2,6-difluorobenzyl alcohol; 1-(2,6-Difluoro-4-ethoxyphenyl)methanol; α-Hydroxymethyl-2,6-difluoro-4-ethoxybenzene
EINECS	Contact for details

Quality Control

Every batch of (4-Ethoxy-2,6-Difluorophenyl)Methanol is produced under strict quality management protocols. We ensure compliance with relevant industry standards through rigorous in-process and final release testing, including identity confirmation, purity assay, and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.