Description

(4-(Difluoromethoxy)-2-Fluorophenyl)Methanol is a high-purity fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its value lies in its unique difluoromethoxy and fluorophenyl structure, which is critical for modulating the physicochemical and metabolic properties of target molecules. This compound is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor in the manufacture of fluorinated compounds for high-performance liquid crystal displays (LCDs).
• Organic Electronics: Employed in the development of novel materials for organic light-emitting diodes (OLEDs) and semiconductor layers.
• Chemical Research & Development: A versatile reagent for introducing the difluoromethoxyphenyl moiety into complex molecular architectures in academic and industrial labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for proprietary client synthesis projects.

Basic Information

Item	Details
Product Name	(4-(Difluoromethoxy)-2-Fluorophenyl)Methanol
CAS No.	438049-76-4
Molecular Formula	C8H7F3O2
Molecular Weight	192.14 g/mol
Synonyms	2-Fluoro-4-(difluoromethoxy)benzyl alcohol; [4-(Difluoromethoxy)-2-fluorophenyl]methanol; 4-(Difluoromethoxy)-2-fluorobenzyl alcohol; 2-Fluoro-α-(difluoromethoxy)toluene; (2-Fluoro-4-(difluoromethoxy)phenyl)methanol; Benzyl alcohol, 2-fluoro-4-(difluoromethoxy)-; DFMPM
EINECS	Contact for details

Quality Control

Every batch of (4-(Difluoromethoxy)-2-Fluorophenyl)Methanol is produced under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (HPLC), with higher purity grades available. Certificates of Analysis (COA) detailing batch-specific results are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.