Description

(3-Chloro-5-(Trifluoromethoxy)Phenyl)Methanol is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its unique molecular architecture, combining chloro, trifluoromethoxy, and hydroxymethyl functionalities, which enables precise structural modifications in target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in CNS and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and insecticides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing aromatic and fluorinated segments into specialty polymers.
• Organic Synthesis Building Block: Utilized in Suzuki, Sonogashira, and other cross-coupling reactions to construct complex polyfunctional arenes.
• Chemical Research: Employed in academic and industrial R&D for exploring new reaction pathways and creating compound libraries for screening.

Basic Information

Product Name	(3-Chloro-5-(Trifluoromethoxy)Phenyl)Methanol
CAS No.	433926-47-7
Molecular Formula	C8H6ClF3O2
Molecular Weight	226.58 g/mol
Synonyms	3-Chloro-5-(trifluoromethoxy)benzyl alcohol; (3-Chloro-5-(trifluoromethoxy)phenyl)methanol; 1-(3-Chloro-5-(trifluoromethoxy)phenyl)methanol; α-Hydroxymethyl-3-chloro-5-trifluoromethoxybenzene; 3-Chloro-α-(hydroxymethyl)-5-(trifluoromethoxy)benzene; 3-Chloro-5-(trifluoromethoxy)benzenemethanol; Benzyl alcohol, 3-chloro-5-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our (3-Chloro-5-(Trifluoromethoxy)Phenyl)Methanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization including HPLC, GC, NMR, and IR to confirm identity and purity. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your internal specifications and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.