Description

4-Oh-E2-1-N3Ade CAS NO 428506-88-1 is a high-purity, synthetic nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis and study of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of antiviral and anticancer drugs. Our supply ensures consistent quality and reliable availability for your critical R&D and manufacturing processes.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel nucleoside-based antiviral and anticancer therapeutics.
• Biochemical Research: Used as a reference standard and probe in enzymatic studies and metabolic pathway analysis.
• Antiviral Drug Discovery: Serves as a core scaffold for designing compounds that target viral polymerases and replication mechanisms.
• Oncology Research: Investigated for its potential to interfere with DNA/RNA synthesis in rapidly dividing cancer cells.
• Academic Research: Employed in university and institutional labs for fundamental studies in medicinal chemistry and molecular biology.
• Process Development: Used in scaling up and optimizing synthetic routes for active pharmaceutical ingredient (API) manufacturing.

Basic Information

Product Name	4-Oh-E2-1-N3Ade
CAS No.	428506-88-1
Molecular Formula	C10H12N6O4
Molecular Weight	280.24 g/mol
Synonyms	4-Hydroxy-E2-1-N3-adenine; 1-N3-Adenine derivative; 4-OH-E2-N3-Ade; 9H-Purin-6-amine derivative; Research Compound 428506-88-1; Nucleoside analog intermediate; Modified adenine base
EINECS	Contact for details

Quality Control

Every batch of 4-Oh-E2-1-N3Ade is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with research and development standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.