Description

1-(4-Fluorophenyl)-5-Methyl-1H-Pyrazole-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound serves as a critical building block for constructing complex molecular architectures, offering a versatile handle for amide bond formation. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyrazole and fluorophenyl pharmacophores.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the creation of labeled compounds and molecular probes for biochemical and diagnostic research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-(4-Fluorophenyl)-5-Methyl-1H-Pyrazole-4-Carbonyl Chloride
CAS No.	423768-49-4
Molecular Formula	C11H8ClFN2O
Molecular Weight	238.65 g/mol
Synonyms	4-Fluorophenyl-5-methyl-1H-pyrazole-4-carbonyl chloride; 1-(4-Fluorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid chloride; 5-Methyl-1-(4-fluorophenyl)-1H-pyrazole-4-carbonyl chloride; 1H-Pyrazole-4-carbonyl chloride, 1-(4-fluorophenyl)-5-methyl-; 423768-49-4; 4-Fluorophenyl-5-methylpyrazole-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)-5-Methyl-1H-Pyrazole-4-Carbonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.