Description

5-Methyl-1-(2-Methylphenyl)-1H-Pyrazole-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters as a key building block for constructing complex heterocyclic molecules, enabling the development of novel active ingredients. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammation.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides, leveraging the pyrazole core for biological activity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling and modifying biomolecules in probe development and bioconjugation strategies.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO laboratory settings.

Basic Information

Product Name	5-Methyl-1-(2-Methylphenyl)-1H-Pyrazole-4-Carbonyl Chloride
CAS No.	423768-42-7
Molecular Formula	C12H11ClN2O
Molecular Weight	234.68 g/mol
Synonyms	1H-Pyrazole-4-carbonyl chloride, 5-methyl-1-(2-methylphenyl)-; 5-Methyl-1-o-tolyl-1H-pyrazole-4-carbonyl chloride; 1-(2-Methylphenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride; 4-Pyrazolecarbonyl chloride, 5-methyl-1-(2-methylphenyl)-; o-Tolyl methyl pyrazole carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 5-Methyl-1-(2-Methylphenyl)-1H-Pyrazole-4-Carbonyl Chloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC for purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.