Description

9-(β-L-Ribofuranosyl)-6-Chloropurine is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and building block for the creation of novel therapeutic agents, particularly in antiviral and anticancer drug discovery pipelines. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the synthesis of modified nucleosides and nucleotides.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies involving purine metabolism and nucleoside-processing enzymes.
• Prodrug Development: Serves as a building block for designing prodrugs with improved bioavailability and targeted delivery.
• Antisense Oligonucleotide Synthesis: Can be incorporated into oligonucleotide chains for medicinal chemistry and molecular biology applications.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Medicinal Chemistry: Utilized in structure-activity relationship (SAR) studies to explore new chemical entities for therapeutic potential.

Basic Information

Product Name	9-(β-L-Ribofuranosyl)-6-Chloropurine
CAS No.	415705-32-7
Molecular Formula	C₁₀H₁₁ClN₄O₄
Molecular Weight	286.67 g/mol
Synonyms	6-Chloro-9-(β-L-ribofuranosyl)-9H-purine; 6-Chloropurine β-L-riboside; 6-Chloro-9-β-L-ribofuranosylpurine; L-6-Chloropurine riboside; 9-(β-L-Ribofuranosyl)-6-chloro-9H-purine; 6-Chloropurine L-riboside; 415705-32-7; 9H-Purine, 6-chloro-9-β-L-ribofuranosyl-
EINECS	Contact for details

Quality Control

Our 9-(β-L-Ribofuranosyl)-6-Chloropurine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.