Description

5-Fluoro-4-Thioxo-1-(β-L-Ribofuranosyl)Uracil is a specialized nucleoside analog with significant potential in pharmaceutical research and development. This compound is valued for its unique structural features, which make it a critical intermediate in the synthesis of novel antiviral and anticancer agents. It is primarily sought by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in the development of nucleoside-based therapeutics and diagnostic probes.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleoside metabolism and DNA/RNA synthesis.
• Antiviral Drug Discovery: Serves as a core scaffold in the research and development of drugs targeting viral polymerases.
• Oncology Research: Investigated for its potential as a prodrug or active metabolite in cancer chemotherapy protocols.
• Diagnostic Probe Development: Utilized in the creation of labeled compounds for molecular imaging and diagnostic assays.
• Academic & Contract Research: Employed in universities and CROs for fundamental studies in medicinal chemistry and chemical biology.

Basic Information

Product Name	5-Fluoro-4-Thioxo-1-(β-L-Ribofuranosyl)Uracil
CAS No.	415705-21-4
Molecular Formula	C9H11FN2O6S
Molecular Weight	294.26 g/mol
Synonyms	4-Thio-5-fluorouridine; 5-Fluoro-4-thiouridine; 1-(β-L-Ribofuranosyl)-5-fluoro-4-pyrimidinethione; 5-Fluoro-4-thio-β-L-uridine; 4-Thio-5-fluoro-β-L-uridine; 5-F-4-ThioUrd; L-5-Fluoro-4-thiouridine
EINECS	Contact for details

Quality Control

We maintain rigorous quality control protocols for our high-purity biochemical intermediates. Production follows cGMP principles where applicable, and each batch is analyzed using advanced techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.