Description

5-Fluoro-1-(β-L-Ribofuranosyl)Cytosine (4-Amino-5-Fluoro-1-β-L-Ribofuranosylpyrimidinone) CAS NO 415704-64-2 is a high-purity nucleoside analog of significant interest in advanced pharmaceutical research and development. This compound serves as a critical building block and reference standard for the synthesis of novel antiviral and anticancer agents, particularly in the development of nucleoside-based therapeutics. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies and metabolic pathway investigations.
• Antiviral Drug Development: Serves as a core scaffold for developing compounds targeting viral polymerases and reverse transcriptases.
• Oncology Research: Investigated for its potential incorporation into DNA/RNA, making it valuable for studying mechanisms of action in cancer cell lines.
• Process Chemistry: Employed in route scouting and scale-up for the production of active pharmaceutical ingredients (APIs).
• Analytical Standard: Provides a high-purity benchmark for quality control (HPLC, NMR) in manufacturing environments.

Basic Information

Product Name	5-Fluoro-1-(β-L-Ribofuranosyl)Cytosine (4-Amino-5-Fluoro-1-β-L-Ribofuranosylpyrimidinone)
CAS No.	415704-64-2
Molecular Formula	C9H12FN3O5
Molecular Weight	261.21 g/mol
Synonyms	4-Amino-5-fluoro-1-β-L-ribofuranosylpyrimidinone; 5-Fluoro-1-β-L-ribofuranosylcytosine; 5-Fluoro-L-cytidine; 5-Fluoro-1-((2R,3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl)pyrimidine-2,4-dione; β-L-5-Fluorocytidine; L-5-FC; 5-Fluoro-1-β-L-ribofuranosyl-cytosine; 5-Fluorocytidine L-isomer
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1-(β-L-Ribofuranosyl)Cytosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤2.0%
Residual Solvents (GC)	Meets ICH guidelines
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.