Description

Benzenemethanol, α-(Aminomethyl)-4-Fluoro-, (Alphar)- (9Ci) is a specialized fluorinated benzylamine derivative, identified by CAS number 408337-09-7, serving as a crucial chiral building block in advanced organic synthesis. Its value lies in the unique combination of a benzylic alcohol, a primary amine, and a fluorine substituent, enabling precise molecular construction for complex targets. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of fluorinated active pharmaceutical ingredients (APIs), including potential candidates for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the research and production of advanced, fluorinated herbicides, fungicides, and pesticides where the fluorine atom enhances bioactivity and environmental stability.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, facilitating the production of enantiomerically pure compounds.
• Peptidomimetics and Bioactive Molecule Research: The amine and alcohol functionalities make it a valuable scaffold for constructing peptide analogs and other biologically active molecules in medicinal chemistry.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that require fluorinated aromatic components for specific properties.

Basic Information

Item	Details
Product Name	Benzenemethanol, α-(Aminomethyl)-4-Fluoro-, (Alphar)- (9Ci)
CAS No.	408337-09-7
Molecular Formula	C8H10FNO
Molecular Weight	155.17 g/mol
Synonyms	(R)-4-Fluoro-α-(aminomethyl)benzyl alcohol; (R)-1-(4-Fluorophenyl)-2-aminoethanol; (R)-2-Amino-1-(4-fluorophenyl)ethanol; (R)-4-Fluoro-α-aminomethylbenzyl alcohol; (R)-FAMP; (αR)-α-(Aminomethyl)-4-fluorobenzenemethanol; (R)-FAMP-OH; (R)-2-Amino-2-(4-fluorophenyl)ethanol
EINECS	Contact for details

Quality Control

Our Benzenemethanol, α-(Aminomethyl)-4-Fluoro-, (Alphar)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.