Description

2-(1-Hexynyl)-n-Methyladenosine is a chemically modified nucleoside derivative, specifically an adenosine analog functionalized with a hexynyl group at the 2-position and a methyl group on the nitrogen. This compound is a valuable synthetic intermediate and research chemical, prized for its role in probing biochemical pathways and developing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry, nucleotide research, and the development of targeted small-molecule drugs.

Application

• Medicinal Chemistry Research: Serves as a key building block for the synthesis of novel adenosine receptor ligands and analogs.
• Biochemical Probes: Used in enzymatic studies and as a tool compound to investigate nucleoside-metabolizing enzymes and signaling pathways.
• Pharmaceutical Intermediate: Acts as a precursor in the multi-step synthesis of potential antiviral or anticancer drug candidates.
• Academic Research: Employed in universities and R&D labs for fundamental studies in organic synthesis and chemical biology.
• Nucleotide Analog Development: Investigated for incorporation into oligonucleotides or as a modified nucleoside with altered biological activity.

Basic Information

Product Name	2-(1-Hexynyl)-n-Methyladenosine
CAS No.	403842-38-6
Molecular Formula	C18H25N5O4
Molecular Weight	375.42 g/mol
Synonyms	2-(1-Hexyn-1-yl)-N-methyladenosine; N-Methyl-2-(1-hexyn-1-yl)adenosine; 2-Hex-1-yn-1-yl-N-methyladenosine; 9-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-(hex-1-yn-1-yl)-6-(methylamino)purine; 2-(1-Hexynyl)-N(6)-methyladenosine; Adenosine, 2-(1-hexyn-1-yl)-N-methyl-
EINECS	Contact for details

Quality Control

Our 2-(1-Hexynyl)-n-Methyladenosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) with batch-specific data is provided with every order to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.