Description

1,4-Benzodioxin-2-Carbonylchloride,2,3-Dihydro-,(2S)-(9Ci) CAS NO 401947-96-4 is a high-purity, chiral organic intermediate characterized by its reactive acid chloride functional group and benzodioxane core structure. This compound is of significant value in pharmaceutical and advanced chemical synthesis, serving as a critical building block for constructing complex molecules with defined stereochemistry. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and functional organic materials with specific optical or electronic properties.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Custom Synthesis: A starting point for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	1,4-Benzodioxin-2-Carbonylchloride,2,3-Dihydro-,(2S)-(9Ci)
CAS No.	401947-96-4
Molecular Formula	C9H7ClO3
Molecular Weight	198.60 g/mol
Synonyms	(2S)-2,3-Dihydro-1,4-benzodioxine-2-carbonyl chloride; (S)-2,3-Dihydrobenzo[b][1,4]dioxine-2-carbonyl chloride; (S)-2,3-Dihydro-1,4-benzodioxin-2-carbonyl chloride; (S)-1,4-Benzodioxan-2-carbonyl chloride; (S)-Chromane-2-carbonyl chloride analog; 401947-96-4; (2S)-2,3-Dihydro-1,4-benzodioxine-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our production of 1,4-Benzodioxin-2-Carbonylchloride,2,3-Dihydro-,(2S)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. The material is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.