Description

3-Pentafluorosulfur Benzoyl Chloride is a high-value, reactive organofluorine building block characterized by the pentafluorosulfur (SF5) functional group. This compound matters for its unique ability to introduce the highly electronegative, thermally stable, and lipophilic SF5 moiety into target molecules, significantly altering their physical and chemical properties. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for synthesizing novel active ingredients, as well as by material scientists developing advanced polymers and liquid crystals.

Application

• Pharmaceutical Intermediate: A key synthon for introducing the metabolically stable SF5 group into drug candidates to enhance lipophilicity, bioavailability, and binding affinity.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides where the SF5 group can improve environmental stability and efficacy.
• Advanced Material Precursor: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers, resins, and liquid crystals with tailored electronic and optical properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create novel ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorine Chemistry Research: An essential reagent for academic and industrial research exploring the chemistry and applications of hypervalent sulfur fluorides.
• Dye and Pigment Modification: Used to fluorinate complex organic molecules, potentially leading to dyes with superior lightfastness and color properties.

Basic Information

Product Name	3-Pentafluorosulfur Benzoyl Chloride
CAS No.	401892-81-7
Molecular Formula	C7H2ClF5OS
Molecular Weight	260.60 g/mol
Synonyms	3-(Pentafluoro-λ6-sulfanyl)benzoyl chloride; Benzoyl chloride, 3-(pentafluorosulfur)-; 3-SF5-Benzoyl chloride; 3-(SF5) Benzoyl Chloride; 3-(Pentafluorosulfanyl)benzoyl Chloride; m-Pentafluorosulfur Benzoyl Chloride; 3-(Pentafluorosulphanyl)benzoyl Chloride
EINECS	Contact for details

Quality Control

Our 3-Pentafluorosulfur Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.