Description

4-(4-Methylpiperazin-1-Yl)Benzoyl Chloride is a high-purity, reactive organic intermediate featuring a benzoyl chloride core functionalized with a methylpiperazine moiety. This compound is of significant commercial importance as a key building block in the synthesis of complex molecules, particularly in the pharmaceutical sector. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of active pharmaceutical ingredients (APIs) and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of various drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its reactive acid chloride group for amide bond formation.
• Chemical Research & Development: Serves as a versatile building block in organic synthesis for creating libraries of compounds in medicinal chemistry and material science.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the scalable production of specific APIs where the 4-(4-methylpiperazin-1-yl)benzoyl moiety is a required structural component.
• Dye and Pigment Intermediate: Can be utilized in the synthesis of specialized dyes and functional pigments due to its aromatic structure and reactive site.
• Ligand and Catalyst Preparation: Acts as a starting material for synthesizing complex ligands used in catalytic systems and coordination chemistry.

Basic Information

Product Name	4-(4-Methylpiperazin-1-Yl)Benzoyl Chloride
CAS No.	401495-67-8
Molecular Formula	C12H15ClN2O
Molecular Weight	238.71 g/mol
Synonyms	4-(4-Methyl-1-piperazinyl)benzoyl chloride; 1-[4-(Chlorocarbonyl)phenyl]-4-methylpiperazine; 4-(N-Methylpiperazino)benzoyl chloride; p-(4-Methyl-1-piperazinyl)benzoyl chloride; 4-(4-Methylpiperazin-1-yl)benzoyl chloride; 401495-67-8; 4-(4-Methylpiperazino)benzoyl chloride
EINECS	Contact for details

Quality Control

Our 4-(4-Methylpiperazin-1-Yl)Benzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and commercial synthesis. We adhere to current Good Manufacturing Practices (cGMP) where applicable. Comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, is performed to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.