Description

5-Isoxazolecarbonyl Chloride, 3-Methyl- (9Ci) is a versatile and reactive heterocyclic acid chloride building block used in advanced organic synthesis. Its primary value lies in enabling the efficient introduction of the 3-methylisoxazole-5-carbonyl moiety, a key structural motif in medicinal chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients, particularly for creating amide and ester derivatives.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the isoxazole ring contributes to biological activity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with unique thermal or chemical properties.
• Peptide Mimetics: Employed to incorporate heterocyclic scaffolds into peptide chains, modifying their stability and binding characteristics.
• Ligand and Catalyst Development: Useful for synthesizing specialized ligands for metal complexes used in catalytic processes.
• Chemical Biology Probes: Facilitates the creation of activity-based probes for studying enzyme function and protein interactions.

Basic Information

Product Name	5-Isoxazolecarbonyl Chloride, 3-Methyl- (9Ci)
CAS No.	49783-72-4
Molecular Formula	C5H4ClNO2
Molecular Weight	145.54 g/mol
Synonyms	3-Methylisoxazole-5-carbonyl chloride; 3-Methyl-5-isoxazolecarbonyl chloride; 5-Carboxy-3-methylisoxazole chloride; 3-Methyl-1,2-oxazole-5-carbonyl chloride; 3-Methylisoxazolyl-5-carbonyl chloride; 3-Methyl-5-isoxazole carboxylic acid chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Isoxazolecarbonyl Chloride, 3-Methyl- (9Ci) is produced and tested under strict quality management protocols to ensure high purity and consistency for sensitive synthetic applications. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.