Description

3β,16α-Bis(Trimethylsiloxy)Androst-5-Ene is a high-purity, organosilicon-protected derivative of androst-5-ene, a key steroid intermediate. This compound is specifically engineered to provide enhanced stability and solubility for advanced synthetic applications in pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the fine chemical and pharmaceutical industries for the synthesis of novel steroid-based therapeutics and reference standards.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs).
• Research Chemical: Used in academic and industrial R&D for studying steroid metabolism, receptor binding, and biological activity.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in steroid analysis.
• Process Chemistry: Employed in route scouting and scale-up processes for the production of specialized steroid derivatives.
• Biochemical Tool: Utilized in the development of assays and diagnostic reagents targeting steroid pathways.

Basic Information

Product Name	3β,16α-Bis(Trimethylsiloxy)Androst-5-Ene
CAS No.	49774-92-7
Molecular Formula	C25H46O2Si2
Molecular Weight	434.81 g/mol
Synonyms	Androst-5-ene-3β,16α-diol, bis(trimethylsilyl) ether; 3β,16α-Bis-O-(trimethylsilyl)androst-5-ene; 3β,16α-Di(trimethylsiloxy)androst-5-ene; 5-Androstene-3β,16α-diol bis(trimethylsilyl) ether; 3β,16α-Bis(trimethylsilyloxy)androst-5-ene; 16α-Trimethylsiloxy-3β-trimethylsiloxyandrost-5-ene
EINECS	Contact for details

Quality Control

Our 3β,16α-Bis(Trimethylsiloxy)Androst-5-Ene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.