Description

1H-Pyrazole-1-Carbonyl Chloride, 3,5-Dimethyl- (9Ci) is a versatile and highly reactive organic building block, specifically a functionalized pyrazole derivative. Its core value lies in its role as a key acylating agent for the synthesis of amides and esters, enabling the efficient construction of complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing pyrazole or amide functionalities for various therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyrazole core contributes to biological activity.
• Organic Synthesis Building Block: Serves as a versatile reagent for introducing the 3,5-dimethylpyrazole-1-carbonyl group into target molecules via nucleophilic substitution reactions.
• Material Science Research: Employed in the development of novel polymers, ligands for catalysis, and functional materials with tailored properties.
• Chemical Biology & Proteomics: Can be utilized as a reactive handle for bioconjugation and labeling of biomolecules in research applications.

Basic Information

Item	Details
Product Name	1H-Pyrazole-1-Carbonyl Chloride, 3,5-Dimethyl- (9Ci)
CAS No.	49652-39-3
Molecular Formula	C6H7ClN2O
Molecular Weight	158.59 g/mol
Synonyms	3,5-Dimethyl-1H-pyrazole-1-carbonyl chloride; 3,5-Dimethylpyrazole-1-carbonyl chloride; 1-Carbonylchloride-3,5-dimethylpyrazole; NSC 403119; 3,5-Dimethyl-1-pyrazolecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-1-Carbonyl Chloride, 3,5-Dimethyl- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.