Description

Pyrimidine, 2-Isothiocyanato- (9Ci) is a versatile heterocyclic building block characterized by its reactive isothiocyanate functional group. This compound is critical for the synthesis of complex molecules in advanced research and development, offering a key handle for introducing thiourea linkages. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly for creating thiourea-based pharmacophores with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where the pyrimidine core is a common structural motif.
• Chemical Biology Probe Development: Utilized for labeling and modifying biomolecules (proteins, nucleic acids) due to the reactivity of the isothiocyanate group with amines.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Organic Synthesis Building Block: Provides a versatile scaffold for constructing more complex heterocyclic systems and fine chemicals in academic and industrial R&D.

Basic Information

Product Name	Pyrimidine, 2-Isothiocyanato- (9Ci)
CAS No.	49573-96-8
Molecular Formula	C5H3N3S
Molecular Weight	137.16 g/mol
Synonyms	2-Isothiocyanatopyrimidine; 2-Pyrimidinyl isothiocyanate; Isothiocyanic acid, 2-pyrimidinyl ester; 2-Pyrimidine isothiocyanate; Pyrimidin-2-yl isothiocyanate; 49573-96-8; NSC 403119
EINECS	Contact for details

Quality Control

Our Pyrimidine, 2-Isothiocyanato- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light); ensure containers are sealed immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.