Description

4-Amino-7-β-D-Ribofuranosyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Methanol is a sophisticated nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound matters because it serves as a critical precursor for the synthesis of novel antiviral and anticancer agents, enabling the exploration of targeted therapeutic mechanisms. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key starting material in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and polymerase function.
• Antiviral Agent Development: Serves as a core scaffold for modifying ribose and base moieties to create potential therapeutics against viral infections.
• Oncology Research: Investigated for its role in creating compounds that interfere with DNA/RNA synthesis in rapidly dividing cells.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, specialized nucleoside derivatives.
• Academic Research: Utilized in universities and research institutes for studying structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	4-Amino-7-β-D-Ribofuranosyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Methanol
CAS No.	49558-38-5
Molecular Formula	C₁₂H₁₆N₄O₅
Molecular Weight	296.28 g/mol
Synonyms	4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-methanol; 4-Amino-5-(hydroxymethyl)-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 7H-Pyrrolo[2,3-d]pyrimidine-5-methanol, 4-amino-7-β-D-ribofuranosyl-; 4-Amino-7-(β-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine-5-methanol; Nucleoside analog intermediate; Pyrrolopyrimidine nucleoside
EINECS	Contact for details

Quality Control

Our 4-Amino-7-β-D-Ribofuranosyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Methanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.