Description

N4-Anisoyl-2'-Deoxycytidine CAS NO 48212-99-3 is a chemically modified nucleoside derivative, specifically a protected form of 2'-deoxycytidine. This compound is of significant value in pharmaceutical research and development, particularly in the synthesis of oligonucleotides and prodrugs where selective protection of the cytosine base is required. It is primarily utilized by research institutions, pharmaceutical companies, and CDMOs engaged in the development of novel therapeutics, including antisense oligonucleotides and nucleotide analogs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of modified oligonucleotides for therapeutic applications.
• Antisense Drug Development: Used in research for creating antisense oligonucleotides that target specific RNA sequences.
• Prodrug Synthesis: Serves as a protected precursor in the design of nucleotide prodrugs to enhance bioavailability and targeting.
• Biochemical Research: Employed in studies investigating DNA/RNA metabolism, enzyme mechanisms, and nucleic acid chemistry.
• Nucleoside Analogue Preparation: A starting material for the preparation of various cytidine analogues with potential antiviral or anticancer activity.
• Labeled Compound Synthesis: Useful for incorporating isotopic labels (e.g., 13C, 15N) into nucleosides for tracer studies.

Basic Information

Product Name	N4-Anisoyl-2'-Deoxycytidine
CAS No.	48212-99-3
Molecular Formula	C₁₆H₁₇N₃O₅
Molecular Weight	331.32 g/mol
Synonyms	N4-Anisoyl-2'-deoxycytidine; 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-4-(4-methoxybenzoyl)amino-2(1H)-pyrimidinone; 2'-Deoxycytidine, N4-(p-anisoyl)-; N4-(4-Methoxybenzoyl)-2'-deoxycytidine; N4-p-Anisoyl-2'-deoxycytidine; N4-(p-Methoxybenzoyl)-2'-deoxycytidine; 4-N-Anisoyl-2'-deoxycytidine; Protected 2'-Deoxycytidine
EINECS	Contact for details

Quality Control

Our N4-Anisoyl-2'-Deoxycytidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.