Description

Prenoxdiazine CAS NO 47543-65-7 is a non-narcotic antitussive agent, specifically a peripheral cough suppressant that acts on the cough receptors in the respiratory tract. This compound is valued for its targeted action in suppressing persistent, dry coughs without central nervous system depression. It is primarily required by the pharmaceutical industry for the formulation of effective cough relief medications, including syrups, tablets, and lozenges, serving global healthcare markets.

Application

• Active Pharmaceutical Ingredient (API) in antitussive medications.
• Formulation of prescription and over-the-counter (OTC) cough syrups and suspensions.
• Manufacturing of solid oral dosage forms such as tablets and capsules for cough suppression.
• Production of medicated throat lozenges and pastilles.
• Research and development of new respiratory therapeutics.
• Reference standard in analytical and quality control laboratories.

Basic Information

Product Name	Prenoxdiazine
CAS No.	47543-65-7
Molecular Formula	C18H20N2O2
Molecular Weight	296.36 g/mol
Synonyms	Prenoxdiazine Hydrochloride; Libexin; Tibexin; Varoxil; 3-(2,2-Diphenylethyl)-5-(2-piperidinoethyl)-1,2,4-oxadiazole; 5-[2-(1-Piperidinyl)ethyl]-3-(2,2-diphenylethyl)-1,2,4-oxadiazole; Prenoxidazine; Oxadiazole derivative
EINECS	Contact for details

Quality Control

Our Prenoxdiazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee supply reliability and quality assurance for your formulations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Microbial Limits	Complies with Ph. Eur.

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.