Description

(R)-Miconazole CAS NO 47447-53-0 is the single enantiomer of the broad-spectrum antifungal agent Miconazole, offering targeted pharmacological activity. This high-purity chiral intermediate is critical for the research and development of enantiomerically pure antifungal pharmaceuticals. It is essential for pharmaceutical manufacturers and research institutions focused on advanced antifungal therapies, chiral drug synthesis, and pharmacological studies to understand stereospecific activity.

Application

• Chiral Pharmaceutical Intermediate: Key building block for the synthesis of enantiomerically pure antifungal drugs.
• Antifungal Agent Research: Used in R&D to study the stereospecific efficacy and mechanism of action of miconazole derivatives.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Asymmetric Synthesis: Employed in advanced organic synthesis to create novel chiral compounds with potential therapeutic value.
• Metabolism and Pharmacokinetic Studies: Utilized in preclinical research to investigate the absorption, distribution, metabolism, and excretion (ADME) of the (R)-enantiomer.

Basic Information

Product Name	(R)-Miconazole
CAS No.	47447-53-0
Molecular Formula	C18H14Cl4N2O
Molecular Weight	416.13 g/mol
Synonyms	(R)-1-(2-(2,4-Dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole; (R)-Miconazole; (R)-(-)-Miconazole; Dexmiconazole; (R)-Miconazole base; UNII-7NNO0D7S5M; (2R)-1-(2,4-Dichloro-β-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
EINECS	Contact for details

Quality Control

Our (R)-Miconazole is manufactured under strict quality management systems. Each batch is tested to ensure high enantiomeric purity and chemical identity, with specifications aligning with research-grade and pharmaceutical intermediate requirements. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and related substances is provided to guarantee traceability and compliance for your R&D and cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.