Description

(S)-Miconazole is the single enantiomer of the broad-spectrum imidazole antifungal agent. This specific stereoisomer is of significant interest in pharmaceutical research and development for its potential enhanced activity and reduced side-effect profile compared to the racemic mixture. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of novel antifungal therapeutics and chiral drug studies.

Application

• Active Pharmaceutical Ingredient (API) in the research and development of enantiomerically pure antifungal medications.
• Key chiral intermediate for the synthesis of advanced antifungal compounds and prodrugs.
• Reference standard in analytical chemistry for quality control and method development in pharmaceutical analysis.
• Biochemical research tool for studying the mechanism of action of imidazole antifungals and sterol biosynthesis inhibition.
• Starting material for the preparation of specialized derivatives for structure-activity relationship (SAR) studies.
• Potential use in topical antifungal formulations under development, such as creams, ointments, and sprays.

Basic Information

Product Name	(S)-Miconazole
CAS No.	47447-52-9
Molecular Formula	C18H14Cl4N2O
Molecular Weight	416.13 g/mol
Synonyms	(S)-1-(2-(2,4-Dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole; (-)-Miconazole; (S)-(-)-Miconazole; Miconazole S-enantiomer; (S)-Miconazole nitrate (salt form); SCZ; R 14889 (S-form); Antifungal agent (S)-enantiomer
EINECS	Contact for details

Quality Control

Our (S)-Miconazole is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet rigorous standards. Certificates of Analysis (COA) detailing specifications such as assay (by HPLC), chiral purity, and related substances are provided and available upon request to support your regulatory and R&D needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.