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7,8-Didehydro-4,5α-Epoxy-6α-Ethoxy-17-Methylmorphinan-3-Ol CAS NO 47252-06-2
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CAS No.:47252-06-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
7,8-Didehydro-4,5α-Epoxy-6α-Ethoxy-17-Methylmorphinan-3-Ol is a specialized morphinan derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analytical study of opioid receptor ligands. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers focused on neuropharmacology and analgesic drug discovery.
Application
- Pharmaceutical Intermediate: A key building block in the synthetic pathways for novel opioid analgesics and antagonists.
- Reference Standard: Used in analytical chemistry for method development, validation, and quality control testing of related active pharmaceutical ingredients (APIs).
- Biochemical Research: Employed in receptor binding assays and pharmacological studies to investigate the structure-activity relationships (SAR) of morphinan compounds at opioid receptors.
- Process Development: Serves as a precursor in the scale-up and optimization of manufacturing processes for specialized pharmaceuticals.
- Metabolite Studies: Utilized as a standard in the identification and quantification of drug metabolites during pharmacokinetic research.
Basic Information
| Product Name | 7,8-Didehydro-4,5α-Epoxy-6α-Ethoxy-17-Methylmorphinan-3-Ol |
| CAS No. | 47252-06-2 |
| Molecular Formula | C19H23NO3 |
| Molecular Weight | 313.39 g/mol |
| Synonyms | 6α-Ethoxy-7,8-didehydro-4,5α-epoxy-17-methylmorphinan-3-ol; 6α-Ethoxy-7,8-didehydro-4,5-epoxy-3-hydroxy-N-methylmorphinan; 6α-Ethoxy-7,8-didehydro-4,5α-epoxy-17-methylmorphinan-3-ol; 6α-Ethoxy-7,8-didehydro-4,5-epoxy-3-hydroxy-N-methylmorphinan; 6α-Ethoxynaltrexol; 6α-Ethoxy-7,8-didehydro-4,5-epoxy-3,14-dihydroxy-17-methylmorphinan (related); 6α-Ethoxy-7,8-didehydro-4,5-epoxy-3-hydroxy-17-methylmorphinan |
| EINECS | Contact for details |
Quality Control
Our 7,8-Didehydro-4,5α-Epoxy-6α-Ethoxy-17-Methylmorphinan-3-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a dry environment and opened under conditions of low humidity to prevent moisture absorption.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to reference spectrum |
| Identification (HPLC) | Retention time matches reference standard |
| Purity (HPLC) | ≥ 98.0% |
| Loss on Drying | ≤ 1.0% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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