Description

1,3-Cyclohexanedicarbonyl Dichloride, trans-(+)- (9Ci) is a high-purity, stereochemically defined diacid chloride derivative. This compound serves as a critical chiral building block and coupling agent in advanced organic synthesis, enabling the precise construction of complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-fidelity intermediates for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting complex molecules.
• Polymer Chemistry: Monomer for the production of specialized polyamides, polyesters, and other condensation polymers with tailored thermal and mechanical properties.
• Peptide Mimetics & Linker Chemistry: Used in the preparation of peptide analogs and as a bifunctional linker for bioconjugation and prodrug strategies.
• Agrochemical Synthesis: Intermediate in the manufacture of advanced, stereospecific herbicides, fungicides, and plant growth regulators.
• Ligand & Catalyst Development: Building block for creating chiral ligands, organocatalysts, and metal-organic frameworks (MOFs).
• Material Science Research: Precursor for advanced organic materials, including liquid crystals and organic semiconductors.

Basic Information

Product Name	1,3-Cyclohexanedicarbonyl Dichloride, trans-(+)- (9Ci)
CAS No.	46065-16-1
Molecular Formula	C8H10Cl2O2
Molecular Weight	209.07 g/mol
Synonyms	trans-(+)-1,3-Cyclohexanedicarbonyl Dichloride; (1R,3R)-1,3-Cyclohexanedicarboxylic Acid Dichloride; (1R,3R)-Cyclohexane-1,3-dicarbonyl Dichloride; trans-1,3-Cyclohexanedicarboxylic Acid Dichloride; Hexahydroisophthaloyl Dichloride, trans-(+)-; (R,R)-1,3-Cyclohexanedicarbonyl Dichloride
EINECS	Contact for details

Quality Control

Our 1,3-Cyclohexanedicarbonyl Dichloride, trans-(+)- (9Ci) is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, identity confirmation by IR and NMR, and assay determination to ensure it meets stringent specifications for research and process use. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, enantiomeric excess, and critical impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with water, strong bases, and alcohols. Keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.