Description

1,2-Cyclohexanedicarbonyl Dichloride, trans-(-)- (9Ci) is a high-purity, stereochemically defined acid chloride derivative of cyclohexane-1,2-dicarboxylic acid. This compound matters as a critical chiral building block for the synthesis of advanced pharmaceutical intermediates and specialty polymers, offering precise control over molecular geometry. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing enantiomerically pure products.

Application

• Pharmaceutical Intermediate: Key chiral precursor for synthesizing active pharmaceutical ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Asymmetric Catalyst Ligand Synthesis: Used in the preparation of chiral ligands for metal-catalyzed asymmetric reactions, enhancing enantioselectivity.
• Specialty Polymer Monomer: Serves as a monomer for producing high-performance, optically active polyamides and polyesters with unique thermal and mechanical properties.
• Agrochemical Synthesis: Building block for creating enantiomerically pure herbicides and pesticides with improved efficacy and environmental profiles.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for complex, chiral molecules in research and development.
• Material Science Research: Used in developing novel chiral stationary phases for chromatographic separation and other advanced functional materials.

Basic Information

Product Name	1,2-Cyclohexanedicarbonyl Dichloride, trans-(-)- (9Ci)
CAS No.	46021-27-6
Molecular Formula	C8H10Cl2O2
Molecular Weight	209.07 g/mol
Synonyms	trans-(-)-1,2-Cyclohexanedicarbonyl Dichloride; (1R,2R)-(-)-Cyclohexane-1,2-dicarbonyl Dichloride; (1R,2R)-1,2-Cyclohexanedicarboxylic Acid Dichloride; trans-1,2-Cyclohexanedicarboxylic Acid Dichloride; Hexahydrophthaloyl Dichloride, trans-(-)-; (R,R)-1,2-Cyclohexanedicarbonyl Dichloride; Chiral Cyclohexane-1,2-dicarbonyl Dichloride
EINECS	Contact for details

Quality Control

Our 1,2-Cyclohexanedicarbonyl Dichloride, trans-(-)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure compliance with high-purity standards for research and synthesis. Certificates of Analysis (COA) with detailed specifications for identity, purity, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis. Keep away from strong bases and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.